tert-Butanol (tert-Butyl Alcohol) 99% / 99.5% / 99.9% CAS No. 75-65-0 Industrial & Pharmaceutical Grade

tert-Butanol, available in 99%, 99.5%, and 99.9% concentrations, is produced via direct hydration of isobutylene or as a by-product of propylene oxide manufacturing . It features excellent solvency power, complete miscibility with water and most organic solvents, and exceptional chemical stability as the simplest tertiary alcohol . As a unique branched alcohol with a compact molecular structure, it is widely used as a chemical intermediate for the production of isobutylene, MTBE, and various tert-butyl derivatives, as well as a solvent in pharmaceutical and industrial applications . Its high purity and consistent quality make it ideal for critical applications requiring precise solvent properties. Each batch is rigorously tested using GC analysis to ensure consistent quality meeting industrial and pharmaceutical standards.

Scope of Application

Used as the primary raw material for the production of high-purity isobutylene through dehydration, which is essential for butyl rubber and other polymers ;
Acts as a chemical intermediate for the synthesis of tert-butyl esters, tert-butyl ethers including MTBE and ETBE fuel oxygenates, and tert-butylphenols for antioxidants and polymerization inhibitors ;
Functions as a denaturant for ethanol in industrial and laboratory alcohol formulations ;
Widely applied as a solvent in pharmaceutical manufacturing for drug synthesis, crystallization, and extraction processes ;
Serves as a solvent in coatings, paints, and varnishes, particularly for water-based formulations due to its complete water miscibility ;
Used in the production of flotation agents, cleaning compounds, and industrial degreasers ;
Acts as an additive in fuels to improve octane rating and reduce engine knocking ;
Functions as a laboratory reagent for organic synthesis, chromatography, and as a non-aqueous titration medium ;
Used in the manufacture of tert-butyl hydroperoxide, an initiator for polymerization reactions ;
Serves as a solvent for the removal of water from organic compounds in azeotropic distillation processes.

Product Features

Acetaldehyde, the raw material of the product, is of biological origin and follows the green natural route. The product is produced using the international leading technology, which fills the gap in process technology in China. The odor and high-temperature stability of the products are superior to those of similar products in foreign countries by adopting the odor-removing and refining technology independently developed by the Company. The content of 1,3-butanediol is over 99.5%, with a high purity. It has better moisturizing and emollient properties in cosmetic formula. The Company adopts advanced analytical instruments such as GC and GC-MS to detect samples, which enables the products to reach the industry standard of cosmetics.

Packaging and Transportation

Available in epoxy-lined steel drums (150kg-160kg), IBC totes, and ISO tanks with heating capabilities for molten handling;

Classified as flammable liquid (Class 3), comply with all transportation safety regulations including UN1120 classification with Packing Group II ;

Safety and Storage

✦ The product should be stored in a cool and ventilated warehouse and kept away from kindling and heat sources.

✦ It should be stored separately from oxidants and acids, and is prohibited to mix them in storage.

✦ The warehouse should be equipped with corresponding varieties and quantities of fire-fighting equipment.

✦ The storage area should be equipped with emergency treatment equipment for leakage and appropriate containment materials.

Product display

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tert-B

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What are the main differences between the available purity grades of tert-Butanol?

The 99% grade is suitable for most industrial applications including isobutylene production, MTBE synthesis, and general chemical manufacturing. The 99.5% grade provides higher purity for pharmaceutical applications and sensitive syntheses where stricter impurity control is required. The 99.9% ultra-high purity anhydrous grade is specifically engineered for critical applications including semiconductor manufacturing, advanced pharmaceutical synthesis, and analytical reference standards where absolute minimal impurities (particularly water and carbonyl compounds) are essential .

What makes tert-Butanol unique among the butanol isomers?

tert-Butanol is unique among the four butanol isomers (n-butanol, sec-butanol, isobutanol, and tert-butanol) due to its tertiary alcohol structure. This structure results in several distinctive properties: complete miscibility with water (unlike the other isomers which have limited water solubility), a high melting point of 25-26°C requiring temperature-controlled handling, resistance to oxidation (tertiary alcohols do not oxidize to aldehydes or ketones under mild conditions), and unique reactivity patterns in dehydration and etherification reactions . These properties make it particularly valuable for specific applications where other alcohols cannot be substituted.

What specifications do you offer for pharmaceutical-grade tert-Butanol?

Our pharmaceutical-grade tert-Butanol meets strict specifications including minimum 99.5% purity, water content <0.1%, acidity (as acetic acid) <0.003%, alkalinity <0.002%, evaporation residue <0.002%, and color ≤10 APHA . For lyophilization applications in pharmaceutical manufacturing, our anhydrous grade offers water content below 0.05% . Certificates of analysis with comprehensive impurity profiling are provided with each shipment, making it suitable for pharmaceutical API synthesis, lyophilization, and other regulated applications.