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2-Pyrrolidinone (Butyrolactam) 99.5% CAS No. 616-45-5 Pharmaceutical & Industrial Grade 1
2-Pyrrolidinone (Butyrolactam) 99.5% CAS No. 616-45-5 Pharmaceutical & Industrial Grade 2
2-Pyrrolidinone (Butyrolactam) 99.5% CAS No. 616-45-5 Pharmaceutical & Industrial Grade 3
2-Pyrrolidinone (Butyrolactam) 99.5% CAS No. 616-45-5 Pharmaceutical & Industrial Grade 4
2-Pyrrolidinone (Butyrolactam) 99.5% CAS No. 616-45-5 Pharmaceutical & Industrial Grade 1
2-Pyrrolidinone (Butyrolactam) 99.5% CAS No. 616-45-5 Pharmaceutical & Industrial Grade 2
2-Pyrrolidinone (Butyrolactam) 99.5% CAS No. 616-45-5 Pharmaceutical & Industrial Grade 3
2-Pyrrolidinone (Butyrolactam) 99.5% CAS No. 616-45-5 Pharmaceutical & Industrial Grade 4

2-Pyrrolidinone (Butyrolactam) 99.5% CAS No. 616-45-5 Pharmaceutical & Industrial Grade

2-Pyrrolidinone, with a minimum purity of 99.5%, is produced via advanced synthesis technology from γ-butyrolactone and ammonia. It features excellent solvency power, high chemical stability, and complete miscibility with water and most organic solvents. As a key pyrrolidone derivative and important chemical intermediate, it serves as the fundamental building block for various pharmaceuticals, agrochemicals, and specialty chemicals. Its unique cyclic amide structure provides exceptional reactivity and solubility characteristics. Each batch is rigorously tested using GC and HPLC analysis to ensure consistent quality meeting pharmaceutical and industrial standards.
Scope of Application
· Used as a key intermediate in pharmaceutical synthesis for producing nootropic drugs such as Piracetam and other cognitive enhancers;
· Acts as a raw material for the production of polyvinylpyrrolidone (PVP) and other pyrrolidone-based polymers;
· Functions as a solvent in the electronics industry for photoresist strippers and cleaning applications;
· Widely applied in agrochemical synthesis for herbicides, fungicides, and insecticides;
· Serves as a reaction medium and solvent in organic synthesis for specialty chemicals and dyes;
· Used in the production of plasticizers, stabilizers, and other polymer additives;
· Acts as a humectant and solubilizer in select personal care and cosmetic formulations.
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    Product Features

    2-Pyrrolidinone is manufactured using state-of-the-art catalytic synthesis and distillation technologies, ensuring ultra-high purity and consistent quality. The product features exceptional chemical reactivity as both an amide and amine precursor, making it invaluable for pharmaceutical and fine chemical synthesis. With a boiling point of 245°C and melting point of 25°C, it exists as a crystalline solid at room temperature with unique handling characteristics. Its cyclic amide structure provides excellent thermal stability while maintaining high reactivity for derivatization. Advanced analytical methods, including GC for purity and HPLC for impurity profiling, are employed to guarantee product quality exceeding 99.5%, with strict control over moisture and residual metals.

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    Packaging and Transportation

    · Available in epoxy-lined steel drums (25kg, 50kg, 200kg) and IBC totes;

    · Heated packaging options available for cold weather transport to maintain liquid state;

    · Customized packaging options available upon request to meet specific customer requirements;

    Safety and Storage

    · Store in a cool, well-ventilated area away from direct sunlight and heat sources;

    · Maintain storage temperature above 30°C to prevent solidification and crystallization;

    · Keep containers tightly sealed to prevent moisture absorption and contamination;

    · Avoid storage with strong oxidizing agents, acids, or bases;

    · Ensure storage area is equipped with fire-fighting equipment and spill containment materials;

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    FAQ

    1
    What are the main applications of 2-Pyrrolidinone in pharmaceutical manufacturing?
    2-Pyrrolidinone is primarily used as a key intermediate in the synthesis of nootropic drugs, particularly Piracetam and its analogs. It serves as the fundamental building block for creating the pyrrolidinone ring structure essential for cognitive-enhancing pharmaceuticals.
    2
    How should 2-Pyrrolidinone be handled and stored considering its melting point?
    With a melting point of 25°C, 2-Pyrrolidinone may solidify at room temperature, especially during cold weather. Storage facilities should maintain temperatures above 30°C to keep the product in liquid state. For solidified material, gentle heating below 50°C with proper mixing can reliquefy the product without quality degradation.
    3
    What purity levels do you offer for 2-Pyrrolidinone?
    We supply 2-Pyrrolidinone with minimum 99.5% purity as standard. Higher purity grades (99.8%+) are available for specialized pharmaceutical applications with additional impurity profiling and documentation.
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    Guan Na
    86-13205415284
    sales@richnowchem.com
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    We specialize in providing chemical solvents and services for all industries.
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