2-Chloropropane (Isopropyl Chloride) 99% / 99.5% / ≥99.7% CAS No. 75-29-6 Industrial & Pharmaceutical Grade

2-Chloropropane, available in 99%, 99.5%, and ≥99.7% concentrations, is produced via advanced hydrochlorination of isopropanol with hydrogen chloride or through the addition of hydrogen chloride to propylene according to Markovnikov's rule [citation:23]. It features high chemical reactivity, rapid evaporation rate, and stability as a volatile organic compound . As a secondary alkyl halide, it is widely used as a chemical intermediate in organic synthesis, a solvent in industrial applications, a pesticide intermediate in agrochemical production, and a reagent in pharmaceutical manufacturing . Its high purity and consistent quality make it ideal for critical applications requiring precise chemical properties. Each batch is rigorously tested using GC analysis to ensure consistent quality meeting industrial and pharmaceutical standards .

Scope of Application

Used as a chemical intermediate in the manufacture of acrylic acid, acrylonitrile, propylene oxide, and isopropylamine through various chemical reactions ;
Acts as a solvent in paints, coatings, printing inks, and industrial cleaning formulations, providing excellent solvency for organic compounds, oils, and resins ;
Widely applied as a pesticide intermediate and raw material in the agrochemical industry for the production of herbicides, fungicides, and insecticides including cypermethrin and toxaphene ;
Functions as an intermediate in pharmaceutical synthesis for drug development and active pharmaceutical ingredient (API) manufacturing ;
Serves as a reagent for alkylation reactions in organic synthesis, where it introduces isopropyl groups into target molecules ;
Used in polymer manufacturing as a component in polyvinyl chloride (PVC) synthesis and other polymer production processes ;
Acts as an extraction agent and solvent in analytical chemistry for isolating organic compounds from complex matrices such as environmental samples and biological fluids ;
Functions as a component in refrigerants and aerosol propellants in specialized applications ;
Serves as a flame retardant additive in plastics and polymer materials ;
Used in gas synthesis and chemical reactions for the production of synthetic gases and industrial chemicals in oil and natural gas refining .

Product Features

2-Chloropropane is manufactured using advanced hydrochlorination and purification technologies, ensuring consistent quality and precise purity control. The product features excellent reactivity as an alkylating agent, with a boiling point of 35-36°C at atmospheric pressure . Its molecular weight of 78.54 g/mol and specific gravity of 0.859-0.8617 g/mL at 25°C offer predictable handling properties . The product exhibits limited solubility in water (3.1 g/L at 20°C) while being miscible with alcohol, ether, benzene, and most organic solvents .

Packaging and Transportation

Available in epoxy-lined steel drums (25kg, 200kg), IBC totes, and ISO tanks ;

Available in smaller laboratory-scale quantities including 100mL, 500mL, 1L, 2.5L, and 100g analytical standards with appropriate packaging ;

Classified as flammable liquid (Class 3) with Packing Group I (highest danger level), comply with all transportation safety regulations including UN2356 classification (UN2456 in some sources) ;

Safety and Storage

✦ The product should be stored in a cool and ventilated warehouse and kept away from kindling and heat sources.

✦ It should be stored separately from oxidants and acids, and is prohibited to mix them in storage.

✦ The warehouse should be equipped with corresponding varieties and quantities of fire-fighting equipment.

✦ The storage area should be equipped with emergency treatment equipment for leakage and appropriate containment materials.

Product display

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What are the primary industrial applications of 2-Chloropropane?

2-Chloropropane is predominantly used as a chemical intermediate in the production of acrylic acid, acrylonitrile, propylene oxide, and isopropylamine . It is also widely used as a solvent in paints, coatings, and industrial cleaning formulations, as a pesticide intermediate in agrochemical manufacturing (including cypermethrin and toxaphene), and as a raw material in polymer production for PVC synthesis . Additional applications include use as an extraction agent in analytical chemistry and as an alkylating reagent in organic synthesis .

How does 2-Chloropropane compare to 1-Chloropropane in terms of reactivity?

2-Chloropropane is a secondary alkyl halide with the chlorine atom attached to a secondary carbon, while 1-chloropropane is a primary alkyl halide. Due to increased steric hindrance at the secondary carbon, 2-chloropropane is generally less reactive than 1-chloropropane in SN2 nucleophilic substitution reactions. However, it is more reactive in SN1 reactions due to the greater stability of the secondary carbocation intermediate. The compound's unique reactivity profile, characterized by its secondary carbon structure, influences its suitability for specific synthetic applications compared to primary and tertiary halides .